Inclusion bodies: not that bad…

Inclusion bodies: not that bad…

The formation of inclusion bodies (IBs) constitute a frequent event during the production of heterologous proteins in bacterial hosts. Although the mechanisms leading to their formation are not completely understood, empirical data have been exploited trying to predict the aggregation propensity of specific proteins while a great number of strategies have been developed to avoid the generation ...

INVESTIGATION OF REASONS THAT IMPLY THE DIMINISHED INCLUSION BODIES IN E. COLI

Inclusion bodies in trachoma.

THE epithelial-cell inclusion, which is characteristically found in the early stages of trachoma was first described by Halberstaedter and Prowazek (1907). Since that time, a considerable literature concerning the nature of these bodies has accumulated. It is generally conceded that they consist of virus particles together with material elaborated by the virus and/or produced by the parasitized...

investigation of reasons that imply the diminished inclusion bodies in e. coli

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Inclusion bodies: a new concept

In the last decades, the understanding of inclusion body biology and consequently, of their properties and potential biotechnological applications have dramatically changed. Therefore, the development of new purification protocols aimed to preserve those properties is becoming a pushing demand.